The association between C-reactive protein/albumin ratio and the risk of cardiovascular events in mainte-nance hemodialysis patients
10.3969/j.issn.1006-5725.2024.01.013
- VernacularTitle:C反应蛋白/白蛋白比值与维持性血液透析患者心血管事件风险的关系
- Author:
Yuanmei MU
1
;
Jiayuan ZHAO
;
Ying ZHANG
Author Information
1. 贵州茅台医院肾内科(贵州仁怀 564500)
- Keywords:
C-reactive protein to albumin ratio;
maintenance hemodialysis;
cardiovascular events;
generalized propensity score;
inverse probability weighting
- From:
The Journal of Practical Medicine
2024;40(1):72-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the association between C-reactive protein/albumin ratio(CAR)and the risk of cardiovascular events in maintenance hemodialysis(MHD)patients.Methods This study enrolled MHD patients who were treated in the blood purification center of the Second Affiliated Hospital of Guangzhou Medical University between August 2016 to December 2019,and the follow-up deadline was March 31,2021.Collected the clinical data of patients who conform to the inclusion criteria,including demographic,complications,primary basic disease,biochemical indicators of the patients who underwent 3 months regular dialysis treatment and the occurrence of cardiovascular events during the follow-up period.The Kaplan-Meier method was used to estimate the probability of cardiovascular incidents in MHD patients.The Cox proportional hazards model based on generalized propensity score weighting(GPSW)was used to estimate the relationship between CAR and cardiovas-cular events in MHD patients.Results A total of 170 eligible objects were included in this study,64 patients with cardiovascular events(37.6%).The Cox proportional hazards model which based on GPSW(HRCAR = 2.087,95%CI:1.085～4.015,P = 0.028),indicated that the hazard ratio of cardiovascular events was 2.087 when the CAR each additional a unit in MHD patients.Conclusion CAR and the risk of cardiovascular events in MHD patients have a significant positive correlation,which can help clinical workers recognize the MHD patients who have high risk of cardiovascular events and intervene in time.
