Observation on the therapeutic effect of LPE combined with semi whole blood replacement for postoperative anemia caused by infection
10.3969/j.issn.1006-5725.2023.24.016
- VernacularTitle:淋巴血浆置换加半全血置换治疗术后感染导致贫血的疗效观察
- Author:
Zhengcui LU
1
;
Zhiyue LUO
;
Bin TANG
;
Lei CHEN
;
Kun DENG
;
Tinglun ZHU
;
Changsong WU
Author Information
1. 黔南民族医学高等专科学校附属医院输血医学科(贵州都匀 558000)
- Keywords:
lymphatic plasma exchange surgery;
lymphocytes;
inflammatory mediators;
anemia
- From:
The Journal of Practical Medicine
2023;39(24):3238-3242
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of lymphatic plasma therapy(LPE)combined with semi whole blood exchange on patients with moderate to severe anemia caused by severe postoperative infection.Methods Thirty patients who developed severe postoperative infections with moderate to severe anemia and were treated with antibiotics for 48 to 72 hours but failed to meet the criteria were divided into an observation group(LPE combined with semi whole blood replacement surgery and antibiotic treatment,n = 15)and a control group(conventional antibiotic anti infection and blood transfusion treatment,n = 15).Evaluation indicators of infection and anemia between and within two groups before and after treatment,and the treatment effect were compared,respectively.Results There was no statistically significant difference in the observation indicators of infection and anemia between the two groups before treatment(P>0.05);After each treatment,there was a statistically sig-nificant difference in the evaluation and observation indicators of infection and anemia between the two groups(P<0.05);Observation group:There was a statistically significant difference in the observation and evaluation in-dicators of infection and anemia before and after treatment within the group(P<0.05);Control group:Compared within the group before and after treatment,there was no significant decrease in WBC,NEUT,and NEU observation indicators,and CRP and PCT observation indicators showed an upward trend,while RBC,HBG,and HCT did not show a significant increase.The difference was not statistically significant(P>0.05);Conclusions The com-bination of LPE and semi whole blood replacement surgery is superior to the conventional treatment regimen of anti-biotics alone for anti-infection and blood transfusion to improve anemia symptoms in the treatment of postoperative severe anemia.
