The effects of arginine on the properties of ClinproTM pit and fissure sealant
10.3969/j.issn.1001-3733.2024.02.007
- VernacularTitle:精氨酸改性ClinproTM窝沟封闭剂对其性能的影响
- Author:
Yu WANG
1
;
Yunyang ZHANG
;
Xianghui XING
Author Information
1. 210008,南京大学医学院附属口腔医院,南京市口腔医院,南京大学口腔医学研究所
- Keywords:
Arginine;
Pit and fissure sealant;
Surface microhardness;
Degree of conversion;
Microleakage
- From:
Journal of Practical Stomatology
2024;40(2):193-197
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of arginine on the mechanic properties of Clinpro? pit and fissure sealant.Methods:Experimental pit and fissure sealants were formulated with arginine at 3％,5％,and 10％(Arg3,Arg5 and Arg10)respectively added into ClinproTM,the surface microhardness(SMH),degree of conversion(DC)and microleakage of the samples were investigated.The morphology of different pit and fissure sealants after curing were observed by scanning electron microscope(SEM).The concentration of arginine released at different time points were analyzed by Liquid Chromatography Mass Spectrometry(LC-MS/MS).Results:The SMH and DC was not statistically different among the groups,the microleakage level in Arg 10 group was higher than that in other groups(P＜0.05),and there was no significant difference among other groups.There were some aggregation of arginine particles in modified agents under SEM.The Arg5 showed a significantly higher release rate of arginine at any time point than Arg3 in 24 hours(P＜0.05).Conclusion:Incorporation of 5％arginine does not affect the physical and mechanical properties of ClinproTM pit and fissure sealant and exhibites good arginine release ability.
