A Meta-synthesis of qualitative studies of treatment experiences in cancer patients receiving immune checkpoint inhibitors therapy
10.3760/cma.j.cn211501-20220706-02143
- VernacularTitle:接受免疫检查点抑制剂治疗的肿瘤患者治疗体验质性研究的Meta整合
- Author:
Xiangmin MENG
1
;
Meimei SHANG
;
Qian WANG
;
Rong YAN
;
Kai JIANG
;
Wenhui LIU
;
Junai XIANG
;
Yuting LIN
;
Min DING
Author Information
1. 山东第一医科大学护理学院，济南 250117
- Keywords:
Neoplasms;
Qualitative research;
Immune checkpoint inhibitors;
Evidence-based nursing;
Treatment experience;
Meta-synthesis
- From:
Chinese Journal of Practical Nursing
2023;39(32):2553-2561
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To synthesize the findings of qualitative research on the treatment experience of cancer patients receiving immune checkpoint inhibitors therapy to provide a basis for developing relevant health education strategies and other supportive care interventions.Methods:Qualitative research on the treatment experience of cancer patients receiving immune checkpoint inhibitors therapy, published by May 2022, were searched in English and Chinese databases, including Cochrane Library, PubMed, Embase, PsycINFO, CINAHL, Web of Science, CNKI, Wanfang, VIP, and CBM. The quality of the included studies was evaluated by Joanna Briggs Institute Critical Appraisal Tool for qualitative studies. The research results were summarized and Meta-synthesis using the pooled integration method.Results:A total of 13 articles were included and 62 findings were grouped into 12 new categories according to their similarities. These 12 categories resulted in 4 synthesized findings: life was affected, facing multiple decision scenarios, presence of some unmet needs and gaining positive experiences and personal growth.Conclusions:Although patients experience some positive experiences, a large proportion of them experience significant health distress. Healthcare professionals should develop targeted health education with supportive care strategies on the basis of a comprehensive assessment.
