Research on risk factors for microcirculation obstruction after acute myocardial infarction reperfusion
10.3969/j.issn.1002-1671.2024.04.011
- VernacularTitle:急性心肌梗死再灌注后发生微循环阻塞的危险因素研究
- Author:
Yuhong GAN
1
;
Zhi YANG
;
Miao WEN
;
Yitian LONG
;
Liangchao GAO
;
Qiong LI
;
Bing FU
Author Information
1. 成都中医药大学医学与生命科学学院,四川 成都 611130
- Keywords:
acute myocardial infarction;
microcirculation obstruction;
cardiac magnetic resonance
- From:
Journal of Practical Radiology
2024;40(4):562-566
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of microcirculation obstruction(MVO)after reperfusion in patients with acute myocardial infarction(AMI).Methods Forty-one patients with AMI who received treatment with myocardial reperfusion were retrospectively selected.Cardiac magnetic resonance(CMR)was used to determine whether the patients had MVO.The patients were divided into MVO and non-MVO groups.The basic data,laboratory examination and CMR parameters of patients were collected and compared between the groups,and the risk factors related to MVO were screened out by logistic regression analysis.Results Delayed myocardial enhancement was observed in all 41 patients,among which 11 cases(26.8%)were with MVO.A total of 206 delayed myocardial enhancement segments were observed,of which 77 segments combined with MVO and 129 segments without MVO.AMI patients with MVO had a higher rate of transmural myocardial infarction,greater infarct volume,left ventricular myocardial mass(LVMM)and edema degree,as well as lower ejection fraction of left and right ventricles(P<0.05).Multivariate logistic regression analysis indicated that infarct volume[odds ratio(OR)=1.116,95%confidence interval(CI)1.017-1.224,P=0.020]was an independent risk factor for MVO after AMI reperfusion.Conclusion Infarct volume is an independent risk factor for MVO after AMI reperfusion,and MVO is associated with left and right ventricular function impairment.
