Evaluation of corpus callosum absence and intracranial accompanying abnormalities via prenatal MRI
10.3969/j.issn.1002-1671.2024.04.004
- VernacularTitle:产前MRI对胼胝体缺如及颅内伴随异常的评价
- Author:
Ting WANG
1
;
Guangmin LI
;
Lili SHI
;
Pengfei SONG
;
Yang ZHAO
;
Surong LI
Author Information
1. 唐山市妇幼保健院放射科,河北 唐山 063003
- Keywords:
fetus;
corpus callosum absence;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2024;40(4):531-534,571
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the absence of corpus callosum(ACC)and intracranial accompanying abnormalities in fetus via prenatal MRI.Methods A total of 61 cases of fetal ACC diagnosed by prenatal MRI were analyzed retrospectively.The types and numbers of intracranial accompanying abnormalities were observed,and the probability of accompanying abnormalities was counted.According to whether the corpus callosum was completely absent,all cases were divided into complete ACC and partial ACC.Statistical differences of probability of accompanying abnormalities between the two groups were analyzed.Results A total of 54.1%(33/61)patients were complicated with other intracranial abnormalities,among which the most common was cerebral cortical dysplasia,accounting for 26.2%(16/61).The probability of complete ACC and partial ACC complicated with other intracranial abnormalities was 63.4%(26/41)and 35.0%(7/20),respectively,and there was statistical difference in intracranial abnormalities between complete ACC and partial ACC(χ2=4.37,P=0.037).The probability of complete ACC and partial ACC complicated with cerebral cortical dysplasia was 39.0%(16/41)and 5.0%(1/20),respectively,and there was statistical difference in cerebral cortical dysplasia between complete ACC and partial ACC(χ2=7.74,P=0.005).Conclusion MRI can accurately diagnose the fetal ACC and intracranial accompanying abnormalities.Complex ACC is more common than isolated ACC.Compared with partial ACC,complete ACC is more likely to be complicated with other intracranial abnormalities,and cerebral cortical dysplasia is the most common,which provides reliable diagnostic basis for fetal prognosis in clinical practice.