The predict value of CT angiography combined with CT perfusion parameters and serum biology for recurrent stroke events
10.3969/j.issn.1002-1671.2024.04.002
- VernacularTitle:CT血管成像联合CT灌注成像参数和血清生物学对卒中复发事件的预测价值
- Author:
Shili HE
1
;
Hongyan LU
;
Rong WU
;
Yuxin HE
;
Gaofeng ZHANG
Author Information
1. 遵义医科大学第二附属医院医学影像科,贵州 遵义 563000
- Keywords:
stroke;
computed tomography angiography;
computed tomography perfusion;
recurrence
- From:
Journal of Practical Radiology
2024;40(4):523-527,547
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predict value of imaging parameters in computed tomography perfusion(CTP)combined with computed tomography angiography(CTA)examination and serum biomarkers for recurrent stroke events at three-month and one-year follow-ups.Methods A total of 136 patients with cerebral infarction diagnosed for the first time were included in the retrospective study.These patients received CTA+CTP one-stop examination and serum biomarkers testing,followed by three-month and one-year follow-ups for the occurrence of recurrent stroke events.Recurrent stroke events were defined as ischemic stroke,retinal infarction,intracerebral hemorrhage,subarachnoid hemorrhage,and death.Results The recurrent stroke events rate was 23.5%(32 cases)and 36.8%(50 cases)at three-month and one-year follow-ups,respectively.Ischemic penumbra(IP)volume[odds ratio(OR)=1.010,P=0.029]and modified Rankin scale(mRS)score at discharge(OR=1.388,P=0.008)were independent predictors for recurrent stroke events at the three-month follow-up,so were lipoprotein(a)[Lp(a)](OR=1.002,P=0.044),vascular stenosis severity(OR=1.489,P=0.029),and mRS score at discharge(OR=1.282,P=0.038)at the one-year follow-up.Conclusion Among patients with stroke diagnosed for the first time,IP volume,Lp(a),vascular stenosis severity and mRS score at discharge are the most powerful predictors of recurrent stroke events at three-month and one-year follow-ups.
