Application value of dual-layer spectral CT 45 keV single energy image in follow up after TACE for hepatocellular carcinoma
10.3969/j.issn.1002-1671.2024.03.032
- VernacularTitle:双层光谱CT 45 keV单能量图像在肝细胞肝癌TACE术后随访中的应用
- Author:
Yan JIANG
1
;
Jie TANG
;
Zhihao FU
;
Yuting TIAN
;
Daixin LI
;
Zhengping XIE
Author Information
1. 南京中医药大学附属南京医院(南京市第二医院)医学影像科,江苏 南京 210003
- Keywords:
hepatocellular carcinoma;
transcatheter arterial chemoembolization;
computed tomography
- From:
Journal of Practical Radiology
2024;40(3):483-486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of dual-layer spectral computed tomography(DLCT)45 keV single energy image in follow up after transcatheter arterial chemoembolization(TACE)for hepatocellular carcinoma(HCC).Methods The DLCT images of 60 patients with HCC after TACE treatment were analyzed retrospectively.The CT value and standard deviation(SD)value of the lesion region of interest(ROI)and surrounding normal liver parenchyma on two kinds of images with 45 keV energy spectrum CT and 120 kVp conventional CT were measured respectively,then the contrast-to-noise ratio(CNR)between the lesions and surrounding normal liver parenchyma was calculated,and their differences were compared.The image quality of the two kinds of images was scored subjectively with the 3-point method,and the patients were divided into different groups according to the enhance-ment degree and tumor staining.The receiver operating characteristic(ROC)curve was also drawn.Results(1)There was no signif-icant difference in CNR between arterial phase,portal phase,and delayed phase of 120 kVp conventional CT(Hc=1.128,P>0.05).The CNR of 45 keV energy spectrum CT was higher than that of 120 kVp conventional CT,with a statistically significant difference(Z=5.060,P<0.05).(2)The subjective score of 45 keV energy spectrum CT was higher than that of 120 kVp conventional CT,and the difference was statistically significant(Z=5.335,P<0.05).ROC curve analysis showed that 45 keV energy spectrum CT had a larger area under the curve(AUC)than 120 kVp conventional CT,and the difference was statistically significant(Z=4.136,P<0.001).Conclusion 45 keV energy spectrum CT image can significantly improve the CNR between tumor and normal liver parenchyma,and it has the better image quality and higher diagnostic efficiency.
