Correlation of abdominal muscle composition and abdominal aortic calcification in maintenance dialysis patients based on quantitative CT
10.3969/j.issn.1002-1671.2024.03.022
- VernacularTitle:基于定量CT研究维持性透析患者腹部肌肉成分与腹主动脉钙化的相关性
- Author:
Hao ZHAN
1
,
2
;
Qichun CHEN
;
Tiantian LIU
;
Dai ZHANG
;
Longsheng WANG
Author Information
1. 安徽医科大学第二附属医院放射科,安徽 合肥 230601
2. 安徽医科大学医学影像研究中心,安徽 合肥 230601
- Keywords:
quantitative computed tomography;
maintenance dialysis;
abdominal aortic calcification;
muscle;
sarcopenia
- From:
Journal of Practical Radiology
2024;40(3):439-442,455
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure the abdominal muscle composition of maintenance dialysis patients using quantitative computed tomography(QCT)and to analyze its relationship with abdominal aortic calcification(AAC).Methods The abdominal CT data of 193 maintenance dialysis patients were analyzed retrospectively and their clinical data were collected.The abdominal muscle composi-tion,including muscle area and muscle fat area,was measured at the middle level of L3 vertebral by QCT.The abdominal aortic calcifica-tion scores(AACs)were calculated using the Agatston method.The groups were grouped according to the quartiles of AACs,and differences in muscle area,muscle fat area and their associated variables were compared between the four groups.The relationship between abdominal muscle composition and AAC was assessed using Spearman rank correlation analysis and partial correlation analysis.Results AACs were positively correlated with age,male,dialysis age,diabetes,hypertension,and abdominal muscle fat area(r=0.555,0.172,0.192,0.348,0.335,0.358,all P<0.05),while no significant correlation was found with abdominal muscle area.A partial correlation analysis controlling for age,sex,dialysis age,hypertension and diabetes showed that AACs were still positively correlated with abdominal muscle fat area(r=0.183,P=0.012).Conclusion Abdominal muscle fat area in maintenance dialysis patients is positively associ-ated with the degree of AAC,and high abdominal muscle fat area is a risk factor for AAC.Enhanced muscle exercise may prevent the risk of vascular calcification in dialysis patients.
