Value of apparent diffusion coefficient in differential diagnosis between dermatofibrosarcoma protuberans and neurofibroma
10.3969/j.issn.1002-1671.2024.03.021
- VernacularTitle:基于表观扩散系数值鉴别诊断隆突性皮肤纤维肉瘤和神经纤维瘤的价值
- Author:
Lingyu GONG
1
;
Ying YUAN
;
Xiaofeng TAO
Author Information
1. 上海交通大学医学院附属第九人民医院放射科,上海 200011
- Keywords:
dermatofibrosarcoma protuberans;
neurofibroma;
magnetic resonance imaging;
apparent diffusion coefficient
- From:
Journal of Practical Radiology
2024;40(3):435-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of differentiating dermatofibrosarcoma protuberans(DFSP)from neurofibroma(NF)based on MR apparent diffusion coefficient(ADC)value.Methods The enhanced MR images data of 50 patients with patho-logically or clinically confirmed DFSP(36 patients)and NF(14 patients)were analyzed retrospectively.Clinical data and characteris-tics of conventional and functional MRI,including maximum diameter,margin,depth of invasion,enhancement pattern,and ADC value,were evaluated and compared between the two groups.Chi square test,independent samples t-test or Mann-Whitney U test were used to select statistically significant parameters.New diagnostic models were established via binary logistic regression analysis.The receiver operating characteristic(ROC)curves were drawn to evaluate the diagnostic performance of these models.Results Univariate diag-nostic models were developed based on age,maximum diameter,and ADC value,while the combined model was established by logis-tic regression analysis.The area under the curve(AUC)of these models were 0.756,0.837,0.826 and 0.923,with sensitivities of 88.89%,80.56%,86.11%and 91.67%,and specificities of 64.29%,85.71%,78.57%and 92.86%,respectively.Conclusion The combined model based on ADC value,age,and maximum diameter is highly valuable for differential diagnosis between DFSP and NF.
