Imaging features of focal nodular hyperplasia-like lesions in the liver of patients undergoing antineoplastic chemotherapy
10.3969/j.issn.1002-1671.2024.03.011
- VernacularTitle:肿瘤化疗患者肝局灶性结节性增生样病变的影像学特征
- Author:
Liang YIN
1
;
Jie GAN
;
Zhangzhu LI
;
Mingyan SHANG
;
Zongchang LI
Author Information
1. 山东省立第三医院影像中心,山东 济南 250030
- Keywords:
antineoplastic chemotherapy;
focal nodular hyperplasia-like lesions;
liver;
computed tomography;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2024;40(3):390-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the imaging manifestations and pathogenesis of liver focal nodular hyperplasia-like(FNH-like)lesions in patients undergoing antineoplastic chemotherapy.Methods The clinical and imaging data of focal nodular hyperplasia(FNH)and FNH-like lesions patients confirmed by pathology after antineoplastic chemotherapy were analyzed retrospectively.Results A total of 67 FNH-like nodules were detected in 15 patients after antineoplastic chemotherapy,including multiple FNH nodules in 8 cases and sin-gle nodule in 7 cases.The mean detected time of FNH-like nodules was(18.9±11.7)months.Central scarring could be observed during follow-up in 5 nodules,and the rest showed atypical FNH features.Among 45 nodules examined with hepatocyte-specific con-trast medium,36 nodules showed slightly high signal in the hepatobiliary phase and other 9 nodules showed isosignal.Conclusion FNH-like lesions in patients during antineoplastic chemotherapy have certain imaging features,such as lack of central scarring,gener-ally smaller nodules,delayed enhancement,and hyperenhancement in hepatobiliary-specific phase,which are of significant value in the diagnosis and differential diagnosis of the disease.
