Diagnostic and predictive value of CT perfusion imaging in patient with traumatic brain injury
10.3969/j.issn.1002-1671.2024.03.003
- VernacularTitle:CT灌注成像在创伤性脑损伤中的诊断与预测价值
- Author:
Anming XIE
1
;
Liuxian WANG
;
Wenfeng WEI
;
Jing ZHA
;
Huagang FAN
;
Ming LIAO
Author Information
1. 中国人民解放军联勤保障部队第九〇八医院放射诊断科,江西 南昌 330002
- Keywords:
traumatic brain injury;
computed tomography perfusion imaging;
Glasgow coma scale;
Glasgow outcome scale-extended
- From:
Journal of Practical Radiology
2024;40(3):356-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of CT perfusion imaging in patient with traumatic brain injury(TBI).Methods Thirty-seven patients with TBI were included retrospectively and divided into mild,moderate,and severe groups according to Glasgow coma scale(GCS)score.Perfusion parameters of the cerebral hemispheres on the injured side and the contralateral side of the level of basal ganglia were compared.After three months,the correlations between perfusion parameters and GCS score at baseline and Glasgow outcome scale-extended(GOSE)score at follow-up were further analyzed,respectively.Results The injured side of TBI patients showed hypo-perfusion compared with that of the contralateral side.The abnormal perfusion volumes of time to maximum of the residual function(Tmax)>10 s was significantly negatively correlated with GOSE score(ρ=-0.55,P=0.01),and could distinguish the good prognosis group from the poor prognosis group with GOSE score[area under the curve(AUC)=0.82,P= 0.01].In the group of patients undergoing decompressive craniectomy,the abnormal perfusion volumes of Tmax>4 s and Tmax>6 s were significantly associated with GCS score(ρ=0.61,P=0.01;ρ=0.53,P=0.03).Conclusion CT perfusion imaging may be useful in assessing the hemodynamics and severity of TBI,and in predicting the clinical prognosis.
