A Meta-analysis of quantitative evaluation of lumbar intervertebral disc degeneration by functional MRI T1ρ
10.3969/j.issn.1002-1671.2024.02.020
- VernacularTitle:功能MRI T1ρ定量评价腰椎间盘退变的Meta分析
- Author:
Gansheng HE
1
,
2
;
Congyang XUE
;
Zhicheng WANG
;
Lin XIE
Author Information
1. 南京中医药大学附属中西医结合医院骨伤科,江苏 南京 210023
2. 南京中医药大学第三临床医学院,江苏 南京 210023
- Keywords:
T1ρ relaxation time;
Pfirrmann grading;
magnetic resonance imaging;
lumbar vertebrae;
intervertebral disc degeneration;
Meta-analysis
- From:
Journal of Practical Radiology
2024;40(2):261-265,310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change rule of T1ρ value in the process of lumbar intervertebral disc degeneration(IVDD)based on Pfirrmann grading by Meta-analysis.Methods PubMed,EMBASE,Cochrane Library,CNKI,Wanfang Data,VIP and Sinomed were searched to collect studies on quantitative assessment of IVDD using T1ρ imaging technology.The retrieval time limit was from the establishment of the database to December 20,2022.Meta-analysis was performed using RevMan 5.4 and Stata 14.0 software.Results A total of 12 articles were included,and the numbers of Pfirrmann grade Ⅰ-Ⅴ lumbar discs were 316,1 460,769,430 and 98,respectively.T1ρ relaxation time decreased gradually with the increase of the grade of degeneration.The T1ρ values of grade Ⅰlumbar discs were significantly higher than those of grade Ⅱ lumbar discs[weighted mean difference(WMD)=14.55,95%confidence interval(CI)6.35-22.75,P<0.01],and the T1ρ values of grade Ⅱ lumbar discs were significantly higher than those of grade Ⅲlumbar discs(WMD=34.20,95%CI 27.05-41.34,P<0.01).The T1ρ values of grade Ⅲ lumbar discs were significantly higher than that of grade Ⅳ lumbar discs(WMD=22.94,95%CI 17.08-28.80,P<0.01).The T1ρ values of grade Ⅳ lumbar discs were significantly higher than that of grade Ⅴ lumbar discs(WMD=9.35,95%CI 6.81-11.89,P<0.01).Conclusion T1ρ imaging technology can objectively and quantitatively evaluate degeneration at different stages,especially sensitive to IVDD in the early and middle stages,which can provide imaging evidence for clinical diagnosis of early IVDD.
