The correlation between preoperative MR imaging features of clear cell renal cell carcinoma and the incidence of metastasis
10.3969/j.issn.1002-1671.2024.02.019
- VernacularTitle:肾透明细胞癌术前MR影像学特征与转移发生率的相关性分析
- Author:
Qiang MA
1
;
Fen WU
;
Min XIA
;
Chuanxian MA
;
Shun CHAI
;
Zhanlong MA
Author Information
1. 南京医科大学第一附属医院放射科,江苏 南京 210029
- Keywords:
clear cell renal cell carcinoma;
metastasis;
magnetic resonance imaging;
apparent diffusion coefficient
- From:
Journal of Practical Radiology
2024;40(2):257-260
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between preoperative MR imaging features and the incidence of tumor metastasis in clear cell renal cell carcinoma.Methods The clinical and preoperative MR imaging data of 64 patients with clear cell renal cell carcinoma were analyzed retrospectively.According to the occurrence of metastasis,the patients were divided into non-metastasis group(n=42)and metastasis group(n=22).The clinical and imaging features of the two groups were analyzed with univariate analysis and multivariate logistic regression.Results The results of the univariate analysis showed that among the clinical and preoperative MR imaging data,there was no significant difference between the two groups in gender,tumor location and intra-tumoral cystic changes(P>0.05),but the patient's ages,clinical symptoms,tumor sizes,necrosis,capsule breakthrough,low signal nodules in T2WI,venous thrombosis,TNM stages,and Fuhrman grades were significantly different between two groups(P<0.05).Multivariate logistic regression analysis showed that low signal nodules in T2WI was an independent predictor of metastasis of clear cell renal cell carcinoma(P=0.028).Combined with diffusion weighted imaging(DWI)sequence,the average apparent diffusion coefficient(ADC)in related areas was measured.The ADC value of low signal nodules area was(0.541±0.101)×10-3 mm2/s in the metastasis group,and the ADC value of non-low signal nodules area was(0.972±0.113)×10-3 mm2/s(P<0.001).Conclusion The metastasis of clear cell renal cell carcinoma is often accompanied by low signal nodules in T2WI in tumors.Combined with the lower ADC value,they can be used as the characteristic imaging features to effectively evaluate the risk of metastasis of clear cell renal cell carcinoma.
