The value of plaque-to-aorta CT value ratio in differentiating coronary lipid and fibrous plaques
10.3969/j.issn.1002-1671.2024.02.010
- VernacularTitle:斑块与主动脉CT值比值鉴别冠状动脉脂质和纤维斑块的价值
- Author:
Yaqi GAO
1
;
Xuechang ZHANG
;
Yao PAN
;
Wei WU
;
Zhaoqian WANG
;
Xixia SUN
;
Shuang PAN
;
Hao WANG
;
Zhiqiang YANG
;
Chongfu JIA
Author Information
1. 大连医科大学附属第一医院心血管放射科,辽宁 大连 116011
- Keywords:
coronary artery;
computed tomography;
angiography;
intravascular ultrasound
- From:
Journal of Practical Radiology
2024;40(2):217-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of plaque-to-aorta CT value ratio(standardized CT value)in differentiating coronary lipid and fibrous plaques,and to preliminarily analyze the stability of the cutoff.Methods Patients who underwent coronary computed tomography angiography(CCTA)and intravascular ultrasound(IVUS)within 1 week were included.The plaque CT value was obtained by measuring the all,four and two short-axis planes,respectively.The CT value of the ascending aorta was measured and standardized(plaque-to-aorta CT value ratio).The receiver operating characteristic(ROC)curves of the standardized and the traditional CT values were drawn.Results A total of 60 patients with 74 plaques were included,35 lipid and 39 fibrous plaques were diagnosed by IVUS.The aorta CT value was significantly correlated with the plaque(r=0.420,P<0.01);the cutoffs for the CT value of all,four and two plaque slices were 55 HU,48 HU and 52 HU,respectively,and all there of the cutoffs of standardized CT value were 0.149;the sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)of four-slice traditional and standardized CT values to differentiate lipid and fibrous plaques were 69%,87%,83%,76%and 91%,82%,82%,91%,respectively.Conclusion Compared with traditional CT value,the standardized CT value can greatly improve the sensitivity and NPV in differentiating coronary lipid and fibrous plaques,while maintaining modest to high specificity and PPV.Furthermore,the cutoff is stable.
