The immediate brain effect of acupuncture at Fengchi in patients with posterior circulation ischemia vertigo:a resting-state functional MRI study
10.3969/j.issn.1002-1671.2024.02.003
- VernacularTitle:针刺风池对后循环缺血性单发性眩晕患者即时效应的静息态功能MRI研究
- Author:
Xiaojia YUAN
1
;
Yu XU
;
Weitao WANG
;
Liqun ZHONG
;
Xiaozhen LI
;
Dan XU
;
Wenlong SHE
;
Zhengguang CHEN
Author Information
1. 北京中医药大学东直门医院放射科,北京 107000
- Keywords:
acupuncture;
posterior circulation ischemia vertigo;
amplitude of low-frequency fluctuation;
functional connectivity;
resting-state functional magnetic resonance imaging
- From:
Journal of Practical Radiology
2024;40(2):186-189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the immediate brain effect of acupuncture at Fengchi using amplitude of low-frequency fluctuation(ALFF)and functional connectivity by the resting-state functional magnetic resonance imaging(rs-fMRI)in patients with posterior circulation ischemia vertigo(PCIV).Methods Twenty patients with PCIV were enrolled.The dizziness handicap inventory(DHI)was used to evaluate the severity of vertigo.The patients were randomly divided into acupuncture group and sham acupoint acupuncture group.Rs-fMRI scan was performed before and after acupuncture.MATLAB-based DPABI 6.1 software was used to analyze rs-fMRI data.Correlation analysis was used between the altered ALFF values and DHI scores.The regions of altered ALFF were taken as seeds to analyze functional connectivity.Results Compared with the sham acupoint acupuncture group,the increased ALFF values were mainly located on the left precuneus,left superior frontal gyrus and left caudate nucleus after acupuncture in the acupuncture group;the decreased ALFF values were mainly located on the left cerebellum and right inferior occipital gyrus.The ALFF value of the left superior frontal gyrus was negatively correlated with the DHI score(P=0.04).The increased functional connectivity was mainly found between left precuneus and the right middle frontal gyrus,the right superior frontal gyrus,the decreased functional connectivity was mainly found between left precuneus and the bilateral paracentral lobule and right cerebellum.Conclusion The ALFF value and functional connectivity are different before and after acupuncture,indicating that the vestibular network,visual and motor brain regions functional activities are changed after needling at Fengchi,which may be the brain functional basis of Fengchi for vertigo in PCIV.
