Analysis of clinical data and imaging features of perioperative acute ischemic stroke with non-small cell lung cancer
10.3969/j.issn.1002-1671.2024.02.001
- VernacularTitle:非小细胞肺癌围术期急性缺血性卒中的临床资料及影像学特征分析
- Author:
Haiwei BAI
1
;
Xiaokun MI
;
Danna WU
;
Ying HAN
Author Information
1. 河北医科大学第四医院神经内科,河北 石家庄 050011
- Keywords:
non-small cell lung cancer;
perioperative;
ischemic stroke;
treatment
- From:
Journal of Practical Radiology
2024;40(2):177-180
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical data and head imaging features of perioperative acute ischemic stroke(POAIS)with non-small cell lung cancer(NSCLC)and to explore the possible risk factors and pathogeneses of it,and to provide evidence for the prevention and treatment of POAIS.Methods Data of patients with primary NSCLC who underwent lung resection and had POAIS was retrospectively collected,and the clinical data of patients with cerebral infarction of large artery atherosclerosis(LAA)and stroke of undetermined etiology(SUE)was compared.Results There were 25 NSCLC patients with POAIS,some of whom had no history of cardiovascular and cerebrovascular diseases,and the proportion was higher in SUE.The most common excision site was left upper lobe,especially in SUE.The pathological stage and type were mainly early stage and adenocarcinoma.Most patients developed POAIS within 7 days after surgery,and mainly mild to moderate.Middle cerebral artery was the main responsible vessel and most patients'cerebral infarction locations≥3.SUE was the most common type of Trial of Org 10172 in Acute Stroke Treatment(TOAST),followed by LAA type.Compared with SUE,more patients had a history of type 2 diabetes(P=0.006)and higher preoperative fasting glucose level(P=0.013)with LAA type.Conclusion Attention should be paid to the prevention of LAA type cerebral infarction in NSCLC patients with type 2 diabetes or preoperative high fasting glucose level,and antithrombotic regimen is selected according to different etiological mechanisms of POAIS.The formation of pulmonary vein thrombosis after lung resection should be prevented and paid attention to.
