Study of resting-state functional MRI on immediate effect regulated by acupuncture on acupoints in patients with migraine without aura
10.3969/j.issn.1002-1671.2024.01.003
- VernacularTitle:针刺组穴调节无先兆偏头痛患者即刻效应的静息态功能MRI探讨
- Author:
Ya'nan ZHANG
1
;
Ni LIU
;
Mengmeng REN
;
Yueying HONG
;
Jianrui ZHANG
;
Lei ZHANG
;
Xuanzhi LUO
;
Huilin LIU
;
Jianwei HUO
;
Fang HAN
Author Information
1. 首都医科大学附属北京中医医院放射科,北京 100010
- Keywords:
migraine;
interictal period;
acupuncture;
immediate effect;
regional homogeneity;
voxel-mirrored homotopic connectivity
- From:
Journal of Practical Radiology
2024;40(1):11-14
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the mechanism of immediate effect regulated by acupuncture on acupoints in patients with migraine without aura(MwoA)during the interictal period.Methods A total of 28 MwoA patients were enrolled and resting-state functional magnetic resonance imaging(rs-fMRI)were performed at baseline and after acupuncture for 30 minutes.Paired t test was used to compare the differences of regional homogeneity(ReHo)and voxel-mirrored homotopic connectivity(VMHC)between two groups.Additionally,the correlation between the changes of rs-fMRI indexes and clinical scores was analyzed.Results In MwoA patients after acupuncture for 30 minutes,the mean regional homogeneity(mReHo)was decreased in the right lingual gyrus and right cere-bellum and was increased in the right middle frontal gyrus,while the z transformation voxel-mirrored homotopic connectivity(zVMHC)was significantly decreased in the bilateral cuneus compared with baseline.There was no significant correlation between imaging data and clinical scales.Conclusion Patients with MwoA after acupuncture for 30 minutes show abnormal ReHo and VMHC in multiple brain regions,which suggest that the mechanism of immediate effect may act through regulating pain-related brain regions.
