The value of preoperative MRI in predicting the pathological response of breast cancer after neoadjuvant chemotherapy
10.3969/j.issn.1002-1671.2023.12.012
- VernacularTitle:术前MRI在预测乳腺癌新辅助化疗后病理反应评估中的价值
- Author:
Qilan HU
1
;
Min HUO
;
Yiqi HU
;
Litong HE
;
Caili TANG
;
Yanjin QIN
;
Tao AI
Author Information
1. 华中科技大学同济医学院附属同济医院放射科,湖北 武汉 430030
- Keywords:
breast cancer;
magnetic resonance imaging;
neoadjuvant chemotherapy;
pathological complete response
- From:
Journal of Practical Radiology
2023;39(12):1962-1966
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the performance of MRI in predicting pathological response of different breast cancer subtypes after neoadjuvant chemotherapy(NAC).Methods The MRI images and postoperative pathological results of 91 patients with breast cancer after NAC were analyzed retrospectively.The correlation between the imaging features of different molecular subtypes of breast cancer and postoperative pathological results was studied,and the diagnostic performance of MRI in predicting pathological response after NAC was evaluated,with postoperative pathological results referred as the diagnostic standard.Results Of 91 patients,27(29.7％)and 35(38.5％)cases were diagnosed as imaging complete response(iCR)and pathological complete response(pCR),respectively.The accuracy of MRI in predicting pathological response after NAC was 84.62％,with 94.64％sensitivity,68.57％specificity,and positive predictive value(PPV)and negative predictive value(NPV)of 82.81％and 88.89％,respectively.Conclusion MRI can accurately predict the pathological response of the human epidermal growth factor receptor-2(HER-2)+and triple-negative breast cancer after NAC.
