Trained immunity and its influence on children′s health
10.3760/cma.j.cn101070-20240119-00039
- VernacularTitle:训练免疫及其对儿童健康的影响
- Author:
Peng HAN
1
;
Kunling SHEN
Author Information
1. 国家儿童医学中心，国家呼吸系统疾病临床医学研究中心，首都医科大学附属北京儿童医院呼吸科，北京 100045
- Keywords:
Child;
Trained immunity;
Non-specific;
Immunological memory
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(2):81-84
- CountryChina
- Language:Chinese
-
Abstract:
Trained immunity has been a novel term in immunology for over a decade, referring to the memory immunity produced by the innate immune system upon re-stimulation.Non-specific training of the immune system enhances the immune defense function and is also involved in allergic inflammation and autoimmune diseases.An increasing number of researchers are focusing on the role of immune training in the prevention, treatment, onset and progression of diseases.This review explains the definition, mechanism, and inducers of immune training and its impact on children′s health and disease, in order to enhance pediatricians′ comprehension of trained immunity.
