Application value of the Status Epilepticus in Pediatric Severity Score and PEDSS in assessing the short-term prognosis of children with status epilepticus
10.3760/cma.j.cn101070-20230302-00172
- VernacularTitle:儿童癫痫持续状态严重程度评分量表与PEDSS评分量表对癫痫持续状态患儿近期预后评估的应用价值
- Author:
Jiechao NIU
1
;
Yu ZHANG
;
Jiandong WANG
;
Haiying LI
;
Mengjiao ZHANG
;
Huiqiong LIU
;
Peisheng JIA
;
Erhu WEI
;
Huaili WANG
Author Information
1. 郑州大学第一附属医院儿童医院儿童重症监护室，河南省儿童神经系统疾病临床诊治中心，河南省儿童癫痫与免疫医学重点实验室，郑州 450052
- Keywords:
Status epilepticus;
Status Epilepticus in Pediatric Severity Score;
PEDSS;
Short-term prognostic assessment;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(1):54-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To validate and compare the value of the Status Epilepticus in Pediatric Severity Score (STEPSS) versus PEDSS in assessing the short-term prognosis of children with status epilepticus (SE).Methods:Clinical data of 152 children with SE hospitalized at the First Affiliated Hospital of Zhengzhou University from January 2020 to December 2022 were retrospectively analyzed.According to the STEPSS and PEDSS scores, children with SE were scored and their prognosis was predicted.Receiver operating characteristic (ROC) curves of the 2 scales in assessing the short-term prognosis of SE in children were plotted, and the area under the curve (AUC), optimal cut-off, sensitivity and specificity were calculated, thus validating and comparing the value of the STEPSS versus PEDSS in assessing the short-term prognosis of children with SE.Results:Of the 152 children with SE, 90 were male and 62 were female, with the age of (5.8±3.9) years (1 month to 15 years). There were 112 cases with good prognosis and 40 cases with poor prognosis, involving 13 deaths.The AUC of STEPSS and PEDSS scores in predicting the death in children with SE were 0.908(95% CI: 0.848-0.967) and 0.887(95% CI: 0.831-0.942), respectively, both with the optimal cut-off value of 4.The sensitivity of STEPSS and PEDSS scores in predicting the death in children with SE were 0.740 and 0.846, respectively, and the specificity were 0.745 and 0.835, respectively.There was no significant difference in predicting the death in children with SE between the 2 scales ( P>0.05). In predicting adverse outcomes, the AUC of the STEPSS and PEDSS scores were 0.869(95% CI: 0.800-0.937) and 0.926(95% CI: 0.873-0.979), respectively, both with the optimal cut-off value of 3.The sensitivity of STEPSS and PEDSS scores in predicting adverse outcomes in children with SE were 0.827 and 0.900, respectively, and the specificity were 0.732 and 0.866, respectively.There was significant difference in predicting the adverse outcomes in children with SE between the 2 scales ( P<0.05). Conclusions:Compared with the STEPSS, the PEDSS has a higher application in predicting the short-term treatment outcome of children with SE, which can be used as a routine method to assess the prognosis of children with SE.
