Progress in diagnosis and treatment of allergic fungal airway disease in children
10.3760/cma.j.cn101070-20230714-00585
- VernacularTitle:儿童过敏性真菌气道疾病诊治进展
- Author:
Peng HAN
1
;
Kunling SHEN
Author Information
1. 国家儿童医学中心，国家呼吸系统疾病临床医学研究中心，首都医科大学附属北京儿童医院呼吸科，北京 100045
- Keywords:
Fungus;
Sensitization;
Child;
Allergic fungal airway disease
- From:
Chinese Journal of Applied Clinical Pediatrics
2024;39(1):25-30
- CountryChina
- Language:Chinese
-
Abstract:
Fungus is one of common allergens in allergic disease that affects the susceptibility, severity, and disease control of allergic airway disease in children.A spectrum of respiratory diseases associated with fungal sensitization has been described as allergic fungal airway disease (AFAD), including severe asthma with fungal sensitization, allergic bronchopulmonary aspergillosis, thunderstorm asthma, and allergic fungal rhinosinusitis.Glucocorticoids, biologics, antifungal therapy, and immunotherapy can reduce the airway inflammation, fungal burden, and tissue damage associated with AFAD.This review introduced fungus, the mechanism of fungal sensitization and the detection, as well as the scope and treatment of AFAD in children, aiming to improve the understanding of AFAD among pediatricians.
