Latest Research Progress in ctDNA Detection for Clinical Diagnosis and Treatment of Non-Small Cell Lung Cancer
10.3969/j.issn.1671-7414.2024.02.035
- VernacularTitle:ctDNA检测在非小细胞肺癌临床诊疗应用中的最新研究进展
- Author:
Zuo LIANG
1
;
Zhiqiang TONG
;
Zhenhua YUE
;
Xiaoming BAI
Author Information
1. 山西医科大学第五临床医学院,太原 030012
- Keywords:
non-small cell lung cancer;
liquid biops;
circulating tumor DNA
- From:
Journal of Modern Laboratory Medicine
2024;39(2):192-197
- CountryChina
- Language:Chinese
-
Abstract:
Non-small cell lung cancer(NSCLC)is a highly lethal malignant tumor that poses a serious threat to human health.Traditional methods for tumor diagnosis and treatment have many limitations.However,circulating tumor DNA(ctDNA)detection,a kind of liquid biopsy technology,has gained widespread attention in the field of NSCLC personalized therapy and monitoring due to its non-invasive,convenient,and comprehensive sensitivity.This article will review the latest research progress of ctDNA detection in the clinical diagnosis and treatment of NSCLC in recent years,including its applications in early screening,disease diagnosis,tumor mutation monitoring,treatment efficacy evaluation,and prognosis assessment.