Accuracy of Polymerase Chain Reaction Based Assays for Trichomonas Vaginitis:A Meta-Analysis
10.3969/j.issn.1671-7414.2024.02.031
- VernacularTitle:聚合酶链反应方法检测阴道毛滴虫准确性的meta分析
- Author:
Xin ZHOU
1
;
Cuilan HUANG
Author Information
1. 岳池县人民医院妇产科,四川广安 638300
- Keywords:
Trichomonas Vaginitis;
polymerase chain reaction;
meta-analysis
- From:
Journal of Modern Laboratory Medicine
2024;39(2):168-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the accuracy of polymerase chain reaction(PCR)based assays for Trichomonas Vaginitis.Methods The research literature on the detection of TV based on PCR method since the establishment of the database to May 30,2023 was retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,VIP Database and PubMed Database.After literature screening and data extraction,Meta-analysis was performed using software RevMan 5.4.1 and web service Meta-Disc 2.0.Results A total of 36 literatures and 16 454 clinical samples were included.The results of meta-analysis showed that the combined sensitivity and specificity of polymerase chain reaction for the detection of TV were 0.972(0.943,0.987)and 0.979(0.968,0.986),respectively,the diagnostic odds ratio was 1 643.398(673.168,4 012.008),the positive likelihood ratio was 46.209(30.549,69.897),and the negative likelihood ratio was 0.028(0.013,0.059).Subgroup analysis showed that clinical samples of different genders would not affect the accuracy of polymerase chain reaction,but the accuracy of different PCR detection methods was different.Conclusion The accuracy of polymerase chain reaction in the detection of TV was high and it has good application value.
