Research Progress of Peripheral Immune Score Based on Blood Biomarkers and Its Application in Non-small Cell Lung Cancer

VernacularTitle:基于血液生物标志物的外周免疫评分及在非小细胞肺癌应用中的研究进展
Author: Xueqi TIAN ¹ ; Jiajun SONG ; Yifeng GU ; Guanjin WU ; Lijing JIAO ; Ling XU
Author Information

1. 上海中医药大学附属岳阳中西医结合医院肿瘤一科,上海 200437
Keywords: non-small cell lung cancer; peripheral immune score; predictive model
From: Journal of Modern Laboratory Medicine 2024;39(1):192-198
CountryChina
Language:Chinese
Abstract: Lung cancer is the malignant tumor with the highest incidence and mortality among the Chinese.Tumor node metastasis(TNM)staging established by the American Joint Committee on Cancer(AJCC)and International Union Against Cancer(UICC)is a commonly used criterion,but it still has limitations in judging the prognosis of non-small cell lung cancer(NSCLC)patients.With the advantages of real-time and convenient sampling,the immune score based on peripheral blood biomarkers have the ability to predict prognosis and efficacy of NSCLC patients,which have been developed and validated in clinical studies.However,clinical impleruentation of peripheral immune scores is still not widely in NSCLC patients.Therefore,this study introduces and evaluates the 6 peripheral immune scores and reviews the reseach progress of them in the treatment of NSCLC.