Research Progress of Didang Decoction in the Treatment of Diabetes and its Complications
10.11842/wst.20221018013
- VernacularTitle:抵当汤治疗糖尿病及其并发症的研究进展
- Author:
Bin LIU
1
Author Information
1. 河南中医药大学 郑州 450046
- Keywords:
Diabetes;
Dudang Tang;
Clinical research;
Mechanism research;
Summarize
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2023;25(12):3980-3988
- CountryChina
- Language:Chinese
-
Abstract:
Derived from the Treatise on Febrile Diseases and Miscellaneous Diseases,Didang Decoction is mainly used to treat the syndrome of lower energizer and blood stasis,which has the effect of purging pathogenic heat,breaking blood and removing stasis,and is just in line with the pathogenesis characteristics of diabetes,which is characterized by excessive dryness and heat,stagnation of blood stasis,so it is widely used in the treatment of diabetes and its complications.This article reviews the mechanism of Didang decoction in treating diabetes and its complications.The study found that this prescription has a good effect in the treatment of diabetes and its complications,and its mechanism may be related to the control of blood sugar and the improvement of islets in diabetes patients β Cell function and insulin resistance,regulation of related inflammatory factors and apoptosis,regulation of related protein pathways,so as to protect vascular endothelial cells,enhance vascular stability,improve vascular permeability,delay diabetes macrovascular and microvascular diseases,improve nerve conduction velocity and other effects.However,at present,the breadth and depth of research on the mechanism of Didang Decoction is still insufficient,and there is a lack of long-term follow-up observation and analysis.This study can provide more scientific research and clinical support for further deepening the research on the prevention and treatment of diabetes and its complications with Didang Decoction.
