Analysis of the Pathogenesis of Depression Based on the Correlation Between Nao Xuanfu and Neurovascular Units
- VernacularTitle:基于脑玄府与神经血管单元的相关性分析郁症的发病机制
- Author:
Bin YU
1
;
Shijing HUANG
Author Information
- Keywords: Depression; Nao Xuanfu; Pathogenesis; Neurovascular unit
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(12):3837-3842
- CountryChina
- Language:Chinese
- Abstract: The purpose of this paper is to analyze the pathogenesis of depression from the correlation between Nao Xuanfu and neurovascular unit(NVU).Previous studies have shown that NVU instability is a common pathophysiological link in the pathophysiological mechanism of depression,which involves neurotransmitters,immunity,inflammation,oxidation,heredity and their interaction,multi-targets,multi-pathways,and more complex.Under the principles of TCM holistic view and syndrome differentiation and treatment,it is considered that there is a great similarity between NVU and Naozhixuanfu.Therefore,this paper verifies the correlation between Nao Xuanfu and NVU from four aspects:morphological structure,energy supply,waste excretion and information exchange,and holds that there is a common connotation between NVU instability and Xuanfu depression,and then discusses the etiology and pathogenesis of depression from the perspective of Nao Xuanfu theory.It is considered that depression is located in the brain,the lesion is in Xuanfu,and the blockage of brain Xuanfu is the core pathogenesis,"communication"should be the most important in the treatment.Through the analogy between Nao Xuanfu and NVU,we look for the same pathogenic link in the seemingly independent pathogenesis,so as to provide new ideas for the clinical research of integrated traditional Chinese and western medicine.On the other hand,applying the pathogenesis of Xuanfu depression to clinical diagnosis and treatment will also provide new ideas for the clinical treatment of depression.
