A Randomized Double-Blind Controlled Clinical Study of Freeze-Dried Saffron Tablets in the Treatment of Primary Dysmenorrhea with Qi Stagnation and Blood Stasis Syndrome
- VernacularTitle:藏红花冻干泡腾片治疗原发性痛经气滞血瘀证的随机双盲对照临床研究
- Author:
Yuan YAO
1
;
Qi XIE
;
Zongyue WU
;
Weiping HUANG
;
Hongwei ZHOU
Author Information
- Keywords: Primary dysmenorrhea; Saffron freeze-dried effervescent tablets; Qi stagnation and blood stasis syndrome; Randomized double-blind control
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(11):3541-3547
- CountryChina
- Language:Chinese
- Abstract: Objective To evaluate the efficacy and safety of saffron freeze-dried effervescent tablets in the treatment of primary dysmenorrhea of qi stagnation and blood stasis,and to provide reference for its clinical application.Methods A prospective,randomized,double-blind,placebo parallel controlled clinical trial was designed.60 patients were randomly divided into treatment group and control group.After 3 months of elution,the patients were treated with saffron freeze-dried effervescent tablets and placebo respectively for 2 menstrual cycles and were followed up for 2 months.Results There was no significant change in the control group before and after treatment,while the symptoms in the treatment group were significantly relieved after treatment,which were significantly different from those before treatment,and no adverse reactions occurred in all subjects.Conclusion Saffron freeze-dried effervescent tablets can effectively treat primary dysmenorrhea of qi stagnation and blood stasis with good long-term efficacy and safety,which is worthy of further clinical study.
