ScMulti-Omics Technology and its Application in Acupuncture Research in Perspective
- VernacularTitle:单细胞多模态组学测序及其在针灸研究中的运用展望
- Author:
Liying LIU
1
;
Qiaofeng WU
Author Information
- Keywords: Acupuncture; Traditional Chinese medicine; Single-cell multimodal omics; Single-cell spatial omics
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(11):3515-3522
- CountryChina
- Language:Chinese
- Abstract: Single-cell multimodal omics(scMulti-omics)technology is a cutting-edge biotechnique for identifying cell type specificity and exploring gene regulation of cellular processes.Based on the combined application of two or more single-cell omics,thirteen scMulti-omics patterns of multi-dimensional and multi-scale were formed.In this paper,we proposed specific paths and strategies for constructing the database for scMulti-omics technology,preprocessing scMulti-omics data,and developing a prediction model.Combining scMulti-omics technology with acupuncture is a beneficial exploration for the modernization and advancement of inter-disciplinary Chinese medicine.The establishment of a prediction model of how acupuncture therapy regulates diseases using scMulti-omics data can infer the heterogeneous landscape of cell-level,which is anticipated to profoundly elucidate the multi-dimensional cell regulation mechanism of acupuncture in the treatment of diseases.
