Systemic Lupus Erythematosus Associated with Interstitial Pneumonia and Achalasia.
10.4046/trd.2008.65.4.323
- Author:
Hye Lee KWON
1
;
Kyung Wook HONG
;
Seung Jin LIM
;
So Young PARK
;
Young Deok BAE
;
Kyung Ho KIM
;
Jeong Hee CHOI
;
Eun Kyung MO
;
Yong Bum PARK
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea. bfspark@medimail.co.kr
- Publication Type:Case Report
- Keywords:
Interstitial pneumonia;
Achalasia;
SLE
- MeSH:
Antibodies, Antinuclear;
Cough;
Dilatation;
Dyspnea;
Esophageal Achalasia;
Esophageal Sphincter, Lower;
Esophagus;
Female;
Fever;
Humans;
Lung;
Lung Diseases, Interstitial;
Lupus Erythematosus, Systemic;
Lymphopenia;
Manometry;
Pericardial Effusion;
Prevalence;
Rare Diseases;
Relaxation;
Thorax;
Young Adult
- From:Tuberculosis and Respiratory Diseases
2008;65(4):323-327
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is a multisystem disorder where the etiology is not clearly known. Symptomatic chronic interstitial pneumonitis is an uncommon manifestation, with a reported prevalence of 3~13%. Achalasia is rare disease that presents with failure in the relaxation of the esophagus sphincter. A 22-year-old woman was admitted to our hospital because of fever, cough and dyspnea. The patient had a history of pericardial effusion and Raynaud's phenomenon. The results of laboratory tests indicated the presence of lymphopenia and included positive antibody tests for antinuclear antibody and anti Sm antibody. A chest X-ray demonstrated the presence of peribronchial infiltration on both lung fields. A Chest CT image showed interlobar septal thickening, ground-glass opacity and a honeycomb appearance in both lung fields and esophageal dilatation with air fluid level. An esophagogram showed the presence of dilated esophagus ends that represented the non-relaxed lower esophageal sphincter. Manometry demonstrated incomplete sphincter relaxation. The case was diagnosed as systemic lupus erythematosus associated with interstitial pneumonia and achalasia.
