Research Process of Polysaccharide and Triterpenoids in Large Varieties of Poria cocos with Homology of Medicine and Food
- VernacularTitle:药食同源大品种茯苓中多糖与三萜研究进展
- Author:
Xuemei PU
1
;
Xue LI
;
Xudong HE
;
Jinbiao HE
;
Zhibo LIU
;
Dan XU
;
Xiaojiao CHEN
;
Fan ZHANG
;
Jie YU
Author Information
- Keywords: Poria cocos polysaccharide; Poria cocos triterpenes; Chemistry; Pharmacological activity; Clinical application
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(7):2561-2573
- CountryChina
- Language:Chinese
- Abstract: Poria cocos is a classic Chinese medicine with homology of food and medicine,which is beneficial to water infiltration,spleen and stomach,calming the heart and calming the mind,etc.It is known as"nine Poria cocos in ten prescriptions".Poria cocos contains polysaccharide,triterpenoids and steroids,among them polysaccharide and triterpenoid are considered as the main active components.Modern studies have shown that Poria cocos polysaccharide triterpenes display pharmacological activities such as anti-tumor,immunomodulatory and anti-oxidation.The dissolution rate of poria cocos and triterpenes was low in the traditional decocting process,and the oral absorption rate of poria cocos was low,but the activity of poria cocos and triterpenes was still very good,indicating the high activity of poria cocos and triterpenes.Therefore,this paper systematically reviews the extraction and separation,structural identification,content determination,structural modification,biosynthesis,pharmacological activity and potential product development value of Poria cocos polysaccharide and triterpenoids,in order to provide literature reference for the development of Poria cocos grand health industry.
