A Study to Draw a Normative Database of Laryngopharynx pH Profile in Chinese.
- Author:
Guijian FENG
1
;
Junyao WANG
;
Lihong ZHANG
;
Yulan LIU
Author Information
1. Department of Gastroenterology, Peking University People's Hospital, Beijing, China. fggods@126.com
- Publication Type:Original Article
- Keywords:
Esophageal pH monitoring;
Gastroesophageal reflux;
Laryngopharyngeal reflux
- MeSH:
Asian Continental Ancestry Group*;
Catheters;
Esophageal pH Monitoring;
Female;
Gastroesophageal Reflux;
Healthy Volunteers;
Humans;
Hydrogen-Ion Concentration*;
Hypopharynx*;
Laryngopharyngeal Reflux;
Male;
Oropharynx;
Volunteers
- From:Journal of Neurogastroenterology and Motility
2014;20(3):347-351
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: To draw a normative database of laryngopharynx pH profile in Chinese subjects. METHODS: Normal volunteers were recruited from "www.Ganji.com" and People's hospital between May 2008 and December 2009. The Restech pH Probes were calibrated in pH 7 and pH 4 buffer solutions according to the manufacturer's instructions. Each volunteer was asked to wear the device for a 24-hour period and was encouraged to participate in normal daily activities. RESULTS: The healthy volunteers consisted of 20 males and 9 females with a median age of 23 years (interquartile range, 21 to 32 years). The 95th percentiles for % total times at pH < 4, pH < 4.5, pH < 5.0 and pH < 5.5 for the oropharynx pH catheter were 0.06%, 1.01%, 7.23% and 27.34%, respectively. The 95th percentile for number of reflux events within the 24-hour period at pH < 4, pH < 4.5, pH < 5.0 and pH < 5.5 were 2.0, 18.0, 107.5 and 284.5, respectively. CONCLUSIONS: This is the first study to systematically assess the degree of reflux detected by the new pH probe in healthy asymptomatic Chinese volunteers and to report normative values in Chinese people. Using an oropharyngeal pH catheter to monitor laryngopharyngeal reflux indicated that in healthy Chinese, reflux should be considered normal if the percent time at pH less than 4.5 is no more than 1%.
