Inflammatory pseudotumor-like follicular dendritic cell sarcoma of the spleen:2 cases report and literature review
10.3969/j.issn.1672-8467.2024.01.020
- VernacularTitle:脾脏炎性假瘤样滤泡树突细胞肉瘤2例及文献回顾
- Author:
Huan DU
1
;
Li-Shuang LIN
;
Zun-Guo DU
;
Jie FAN
;
Yun BAO
;
Feng TANG
;
Yuan-Yuan CHENG
Author Information
1. 复旦大学附属华山医院病理科 上海 200040
- Keywords:
spleen;
inflammatory pseudotumor(IPT);
Epstein-Barr virus(EBV)
- From:
Fudan University Journal of Medical Sciences
2024;51(1):128-132
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory pseudotumor-like follicular dendritic cell sarcoma(IPT-like FDCS)is a very rare malignant tumor that is considered to be associated with Epstein-Barr virus.Two patients in this report were generally healthy,and the spleen tumor was found during physical examination.After completing the examination,laparoscopic total splenectomy was performed,and the pathological result showed IPT-like FDCS.Postoperative chemoradiotherapy was not performed in either case.The disease has no characteristic clinical manifestations,and imaging overlaps with sarcoma.Microscopic manifestation showed CD21,CD23 and EBER positive spindle tumor cells in the inflammatory background with matted arrangement.Due to the interwoven distribution of tumor cells and lymphocytes,diagnosis is difficult.In this article,we report this two cases with literature review and summarize their clinical and pathological features to improve diagnostic cognition.
