Research progress of multiple myeloma associated infection

VernacularTitle:多发性骨髓瘤合并糖尿病患者相关感染研究进展
Author: Fengjin JIANG ¹ ; Xue HU ; Xiaodan PENG
Author Information

1. 重庆市渝北区人民医院输血科，重庆　401120
Keywords: Diabetes; Multiple myeloma; Infection; Antimicrobial prophylaxis
From: Chinese Journal of Endocrine Surgery 2023;17(5):638-640
CountryChina
Language:Chinese
Abstract: Infection is one of the most common causes of death in patients with multiple myeloma, which can lead to early death. The incidence of infection in patients with (multiple myeloma, MM) complicated with diabetes is further increased. Proteasome inhibitors, immunomodulatory drugs and other new drug therapy improve the prognosis of MM, but glucocorticoids used in combination chemotherapy are easy to induce glucocorticoid diabetes, lead to elevated blood glucose, increase the risk of MM infection, and affect the prognosis of patients. This article reviews the relationship between infection and disease progression in patients with MM complicated with diabetes mellitus, infection-related factors, and prevention and treatment measures of different types of pathogen infection.