One case report of a patient with anti-osteoporosis drug related hyperparathyroidism cured after strengthening calcium and vitamin D supplementation
10.3760/cma.j.cn.115807-20230615-00174
- VernacularTitle:加强补充钙和维生素D治疗抗骨质疏松药相关甲状旁腺功能亢进一例报道
- Author:
Liyuan MU
1
;
Lingquan KONG
;
Kainan WU
Author Information
1. 重庆医科大学附属第一医院乳腺甲状腺外科，重庆 400016
- Keywords:
Osteoporosis;
Anti-osteoporosis drug;
Hyperparathyroidism;
Vitamin D;
Calcium
- From:
Chinese Journal of Endocrine Surgery
2023;17(4):511-512
- CountryChina
- Language:Chinese
-
Abstract:
Anti-osteoporosis drug is important to treat osteoporosis. However, systemic musculoskeletal and joints pain and other adverse events in some patients are unrelieved or even aggravated after using anti-osteoporosis drugs, which may be associated with anti-osteoporosis drug related parathyroid hyperfunction or hyperparathyroidism. We report a case of 78 years old female with osteoporosis who, on the basis of conventional regular supplementation of Vitamin D and calcium supplements, presented with a decreased level of serum calcium and negative calcium balance after receiving anti-osteoporosis drugs, resulting in hyperparathyroidism, significant pain in bilateral knee joints and inability of walking independently. After sufficient supplementation of vitamin D and calcium, the pain was significantly relieved, bone metabolism indicators returned to normal, the patient was able to walk without assistance and had no recurrence after 1 year of follow-up.
