Predictive value of dual-phase enhanced CT for central lymph node metastasis in papillary thyroid microcarcinoma
10.3760/cma.j.cn.115807-20220704-00178
- VernacularTitle:双期增强CT对甲状腺微小乳头状癌中央区淋巴结转移的预测价值
- Author:
Tong ZHANG
1
;
Min TIAN
;
Yanyan SHU
;
Peiying WEI
;
Zhijiang HAN
Author Information
1. 浙江中医药大学第四临床医学院，杭州 310053
- Keywords:
Thyroid microcarcinoma;
Papillary thyroid microcarcinoma;
Central lymph node metastasis
- From:
Chinese Journal of Endocrine Surgery
2023;17(4):425-429
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of dual-phase enhanced CT for central lymph node metastasis (CLNM) in papillary thyroid microcarcinoma (PTMC) .Methods:The CT data of 220 central lymph nodes in 182 cases of PTMC confirmed by surgery and pathology were retrospectively analyzed. The lymph nodes were divided into 0.3 cm-0.4 cm group, 0.4 cm-0.5 cm and ≥ 0.5 cm groups according to the size of them. The CT values of arterial phase and venous phase of lymph nodes were measured, respectively. The distribution of dual-phase CT values of lymph nodes in the three groups was analyzed by t test. The optimal threshold values of dual-phase enhanced CT values of lymph nodes in each group were obtained by receiver operating characteristic (ROC) . Results:The area under ROC curve of arterial phase CT in predicting CLNM was 0.717, 0.707 and 0.761, the optimal threshold was 71.4Hu, 63.3Hu and 72.9Hu, and the sensitivity and specificity were 50.0% and 92.3%, 63.6% and 81.0%, 52.4% and 82.9%, respectively. The area under the ROC curve of venous phase CT value in predicting CLNM was 0.744, 0.729, and 0.662, the optimal thresholds were 71.1 HU, 80.3 HU, and 61.3 HU, and the sensitivity and specificity were 52.8% and 87.2%, 54.2% and 86.7%, 82.6% and 46.7%, respectively. The sensitivity and specificity of dual-phase combined CT values in predicting CLNM in 3 groups were 44.1% and 94.7%, 50.0% and 88.1%, 52.4% and 85.4%, respectively.Conclusion:Dual-phase enhanced CT can effectively predict central lymph node metastasis of PTMC, and the combination of the two can further improve the specificity of predicting CLNM and provide an important basis for reducing unnecessary surgical trauma.
