Research and clinical progress of immunotherapy for gastric cancer
10.3969/j.issn.1005-6483.2024.01.027
- VernacularTitle:胃癌免疫治疗的临床研究进展
- Author:
Tao HUANG
1
;
Anxin WANG
;
Guang FU
Author Information
1. 430081 武汉,武汉科技大学附属普仁医院胃肠外科
- Keywords:
gastric cancer;
immunotherapy;
immune checkpoint inhibitors;
adoptive cell therapy;
tumor vaccine
- From:
Journal of Clinical Surgery
2024;32(1):99-102
- CountryChina
- Language:Chinese
-
Abstract:
Due to the limited treatment options of advanced gastric cancer and prone to chemoresistance,there is an urgent need for novel treatment methods to improve the prognosis of these patients.At present,immunotherapy including immune checkpoint inhibitor,adoptive cell therapy,tumor vaccine,nonspecific immune enhancer and cytokine therapy has shown good curative effect on gastric cancer.Additionally,carrier drugs and 3D printing technology have also achieved curative effects in preclinical experiments.Clinical trials used immunooncology monotherapy or combined immunochemotherapy to improve the overall survival time and objective response rate of patients with gastric cancer.Based on the preliminary evidence,we believe that immunotherapy can positively affect the natural history and improve the prognosis of patients with gastric cancer.
