A Meta-analysis on the outcome of Solid Hemangioblastomas treated by surgery combined with preoperative endovascular embolization
10.3969/j.issn.1005-6483.2023.12.006
- VernacularTitle:术前辅助栓塞联合开放手术治疗实性血管母细胞瘤疗效的Meta分析
- Author:
Xiangji LI
1
,
2
;
Yanting LIU
;
Zhixian WAN
;
Yuefeng ZHU
;
Chunlei TIAN
Author Information
1. 443003 湖北宜昌,三峡大学神经病学研究所
2. 三峡大学第一临床医学院/湖北省宜昌市中心人民医院神经外科
- Keywords:
preoperative embolization;
surgery;
solid;
hemangioblastomas;
meta-analy-sis
- From:
Journal of Clinical Surgery
2023;31(12):1130-1133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety of preoperative endovascular embolization of Solid Hemangioblastomas.Methods The data bases including Wan Fang,CNKI(China National Knowledge Infrastructure),VIP Database,PubMed、Medline、Springer were searched for the related studies.Two independent surgeons assessed trails for eligibility and quality,and all data marching the standards were abstracted for Meta-analysis by RevMan 5.3.Results 8 randomized controlled trails(RCT)were included.Selected analysis of embolized and non-embolized groups of Solid Hemangioblastomas were observed for variables of clinical efficacy in surgery time,number of blood loss and transfusions,complete resection,there were statistical difference.(P＜0.000 01,WMD=-1.18,95％CI[-1.16,-0.71];P＜0.000 01,WMD=-464.17,95％CI[-492.17,-437.24];P＜0.000 01,WMD=-238.81,95％CI[-282.84,-194.77];P＜0.006,RR=1.17,95％CI[1.05,1.31]).Conclusion The preoperative endovascular embolization is beneficial for Hemangioblastomas because it can shorten the time of surgery,diminish the necessity of intra-operative blood loss and transfusion,it also raises the ratio of complete resection of Solid Hemangioblastomas.
