Research progress of immune regulation and targeted therapy in the inflammatory response of atherosclerotic plaque
10.3969/j.issn.1004-1648.2024.02.027
- VernacularTitle:免疫调控及靶向治疗在动脉粥样硬化斑块炎症反应中的研究进展
- Author:
Jie MA
1
;
Yi LIU
;
Jinpeng OU
Author Information
1. 030012 太原,山西医科大学第五临床医学院
- Keywords:
stroke;
atherosclerotic plaque;
immunoregulation;
inflammatory reaction;
targeted therapy
- From:
Journal of Clinical Neurology
2024;37(2):157-160
- CountryChina
- Language:Chinese
-
Abstract:
Stroke has a high morbidity,disability and mortality.Early identification and intervention of carotid atherosclerotic plaque can prevent the occurrence of stroke.Studies have shown that atherosclerotic plaques are closely related to immune-mediated inflammation,and targeted inflammation therapy is expected to become a new method for the treatment of atherosclerotic plaques.This article systematically reviewed the role of immune regulatory mechanisms of different cells in the inflammatory response of atherosclerotic plaques,as well as potential targeted anti-inflammatory drugs,in order to provide reference for the clinical treatment of atherosclerosis related diseases.