Etiology and outcome of new-onset status epilepticus in older patients
10.3969/j.issn.1004-1648.2024.02.005
- VernacularTitle:老年新发癫痫持续状态的病因及预后
- Author:
Binlu DENG
1
;
Qi WANG
;
Jie YANG
Author Information
1. 610072 成都,四川省医学科学院·四川省人民医院,四川省精神医学中心
- Keywords:
older patients;
new-onset status epilepticus;
etiology;
outcome
- From:
Journal of Clinical Neurology
2024;37(2):91-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the etiology and outcome of elderly patients with new-onset status epilepticus(NOSE).Methods According to the electronic medical record,the keywords"Epilepsy"and"Status epilepticus"were searched for elderly patients with status epilepticus admitted to Sichuan Provincial People's Hospital between January 2018 and June 2023.Elderly patients with NOSE were strictly screened according to inclusion and exclusion criteria,and etiology were analyzed according to medical history and ancillary examinations,and factors related to prognosis of epilepsy were analyzed by Logistic regression.Results There were 63 elderly NOSE patients,including 38 males and 25 females,with an average age of(72.71±7.45)years old.Cerebrovascular disease(21%)was determined as the major cause of NOSE in elderly patients,followed by central nervous system infection(17%).Logistic regression analysis of prognostic factors showed that co-infection(OR = 11.67,95%CI:1.391-97.850,P =0.024)and renal insufficiency(OR =18.90,95%CI:3.522-101.43,P = 0.001)were associated with poor patient prognosis.Conclusions Cerebrovascular disease is the main known cause of NOSE in elderly patients.Prevention of infection and improvement of renal function may improve prognosis.
