Association between intraoperative hypotension and postoperative acute kidney injury in patients un-dergoing brain tumor resection
- VernacularTitle:脑肿瘤患者术中低血压与术后急性肾损伤的相关性
- Author:
Qianyu CUI
1
;
Jiaxin LI
;
Tingting MA
;
Xingyue ZHANG
;
Shu LI
;
Min ZENG
;
Yuming PENG
Author Information
- Keywords: Acute kidney injury; Brain tumor; Intraoperative hypotension
- From: The Journal of Clinical Anesthesiology 2024;40(2):160-164
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the association between intraoperative hypotension and post-operative acute kidney injury(AKI)in patients undergoing brain tumor resections.Methods A total of 428 patients undergoing elective craniotomy for tumor resection were selected,276 males and 152 females,aged≥18 years,BMI 15-36 kg/m2,ASA physical statusⅡ orⅢ.Based on postoperative occurrence of AKI,the patients were divided into two groups:the AKI group and the control group.This study defined three thresholds for hypotension,including MAP during surgery below 65 mmHg,60 mmHg,and 55 mmHg.Multivariate logistic regression was used to analyze the correlation between intraoperative hypotension and postoperative AKI under three thresholds.Results A total of 107 patients had postoperative AKI.The re-sults of multivariable regression analysis indicated that intraoperative MAP＜65 mmHg(OR = 1.11,95%CI 1.03-1.20,P = 0.010)and intraoperative MAP＜60 mmHg(OR = 1.12,95%CI 1.02-1.23,P = 0.017)were associated with postoperative AKI.Conclusion Intraoperative MAP＜65 mmHg or 60 mmHg is associated with postoperative AKI in patients undergoing brain tumor resection.
