Analysis of the epidemic characteristics of common allergens in 10 664 patients in Zhengzhou area from 2013 to 2021
10.13602/j.cnki.jcls.2024.01.04
- VernacularTitle:2013-2021年郑州地区10664例患者常见过敏原流行特征分析
- Author:
Shuhong TAI
1
;
Yuanyu WEI
;
Xiaoyan SONG
;
Yuan WANG
;
Chao NIU
;
Peng WANG
Author Information
1. 郑州大学第三附属医院/河南省妇幼保健院检验科,郑州 450052
- Keywords:
allergy;
allergen;
immunoglobulin E;
retrospective analysis
- From:
Chinese Journal of Clinical Laboratory Science
2024;42(1):18-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To invesitgate the epidemiological characteristics of common allergens in 10 664 patients with allergic diseases in Zhengzhou area.Methods A total of 10 664 patients visited our hospital and underwent serum allergen screening during January 2013 and August 2021 were selected,and their serum sIgE results were retrospectively analyzed.Results The total positive rate of sIgE to allergens in 10 664 patients was 69.82%.The positive rate of sIgE to inhalant allergens was significantly higher than that to in-gestive allergens(χ2=99.15,P<0.01).The top three inhalant allergens were grass and tree combination,dust mite combination,and cockroach.The top three ingestive allergens were egg protein,milk,and seafood combination.The positive rate of sIgE to ingestive al-lergens in males was significantly higher than that in females(χ2=8.18,P<0.01).The highest positive rate of sIgE to ingestive aller-gens was found in the early childhood period(χ2=125.92,P<0.05).The highest positive rate of sIgE to inhalant allergens was found in the school-age and preschool periods(χ2=283.76,P<0.01).The proportions of sIgE to cockroach and house dust mite showed a de-creasing trend year by year,while the proportions of sIgE to milk,peanut,lamb,and seafood combination showed an increasing trend year by year.Conclusion The top three inhalant and ingestive allergens in Zhengzhou area are grass and tree combination,dust mite,cockroach and egg protein,milk,seafood combination,respectively.In recent years,the allergies to milk,peanut,lamb,and seafood should be paid attention.