Research Progress on Paradoxical Extraintestinal Manifestations of Biologics in the Treatment of Inflammatory Bowel Disease
10.12259/j.issn.2095-610X.S20240223
- VernacularTitle:生物制剂在炎症性肠病治疗中的矛盾性肠外表现研究进展
- Author:
Zhangqin LI
1
;
Qi HUANG
;
Yinglei MIAO
Author Information
1. 昆明医科大学第一附属医院消化内科,云南昆明 650032
- Keywords:
Inflammatory bowel diseases;
Paradoxical extraintestinal manifestations;
Biologics
- From:
Journal of Kunming Medical University
2024;45(2):160-165
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory Bowel Diseases(IBD)is a class of genetically related diseases caused by multiple genes and environmental factors that accelerate the disturbance of the immune-gut-microbiome axis.Lesions often involve multiple organs and systems.Biological agents are an important means of treating IBD and its extraintestinal manifestations.Current studies suggest that biologics can bring benefits to patients,but paradoxical skin lesions,joint lesions,and ocular lesions appear during the treatment.Diseases,pulmonary lesions and other manifestations or lesions are easily ignored in clinical practice,thereby delaying the patient's condition and affecting the patient's quality of life.Therefore,by summarizing the clinical characteristics and diagnosis and treatment experience of contradictory extraintestinal manifestations in the current application of biological agents,this review aims to improve the understanding of clinicians,identify this clinical manifestation early,and avoid delaying the patient's condition.
