Clinical and Pathological Characteristics of Extrapleural Solitary Fibrous Tumor
10.12259/j.issn.2095-610X.S20240117
- VernacularTitle:胸膜外孤立性纤维性肿瘤的临床病理特征分析
- Author:
Ying LIU
1
;
Shujie SONG
;
Lin WU
Author Information
1. 昆明医科大学第三附属医院病理科,云南 昆明 650118
- Keywords:
Extrapleural solitary fibrous tumor;
Histological morphology;
Biological behaviour;
Clinical prognosis
- From:
Journal of Kunming Medical University
2024;45(1):100-106
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological characteristics of the extrapleural solitary fibrous tumor and the relevant differential diagnosis.Methods HE and immunohistochemical staining were performed on 26 samples of isolated fibrous tumors outside the pleura,and a comprehensive analysis was conducted based on the clinical and imaging data.Results The histological morphology of isolated fibrous tumors was diverse,with typical cases showing the irregular arrangement of oval or spindle shaped cells.In the stroma,thick collagen bands,antler like blood vessels,and peritubular transparent degeneration could be seen.The immunohistochemical staining demonstrated that the positive rates of STAT-6、CD34、Bcl-2、CD99、SMA were 96.2% 、92.3% 、92.3% 、76.9% and 26.9%,respectively.Conclusion SFT commonly occurs in the pleura and can also occur in other areas.Its histological characteristics and immunohistochemical phenotype help to clarify the diagnosis.However,when it occurs in uncommon anatomical sites,it is necessary to carefully and meticulously distinguish and comprehensively judge the clinical prognosis of key diseases that need to be distinguished or excluded..
