Investigation and Analysis of Vitamin K Level Distribution in 1177 Infants of Different Age Groups
10.12259/j.issn.2095-610X.S20240114
- VernacularTitle:不同年龄段婴儿1177例维生素K1与K2水平分布调查分析
- Author:
Jinyan ZHOU
1
;
Kerong LI
;
Yan MA
;
Jiqiang WANG
;
Zhengming ZHANG
;
Wang LI
Author Information
1. 昆明医科大学附属延安医院儿科,云南 昆明 650051
- Keywords:
Vitamin K1;
Vitamin K2;
Horizontal distribution
- From:
Journal of Kunming Medical University
2024;45(1):83-86
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distributions of vitamin K1 and K2 in infants of different age groups by comparing the serum levels of vitamin K1 and K2 in them.Methods 1177 infants from 0 to 3 months were divided into 6 age groups.Those born/treated in the subject units(pediatrics,neonatology,child health care,obstetrics)were selected as the study subjects and grouped by age:0～3 days(591 cases),4～7 days(255 cases),8～5 days(104 cases),1 month(118 cases),2 months(40 cases),and 3 months(69 cases).General data of the infants were collected,and the serum vitamin K1 and K2 levels were determined by HPLC-mass spectrometry(LC-MS)on a unified platform,and analyzed from the distribution of vitamin K1 and K2 at different ages.Results The distributions of vitamin K1 and K2 levels were statistically significant(P<0.001);newborns were highly vulnerable to vitamin K1 deficiency,and vitamin K2 deficiency was higher than vitamin K1 with age.Conclusion Maintaining the normal growth of vitamin K1 and K2 is crucial for the normal growth and development of infants of all ages,so we should pay close attention to the monitoring and supplement of vitamin K1 and K2.
