Epidemiology of CRKP Infection Outbreak in a Neonatal Intensive Care Unit
10.12259/j.issn.2095-610X.S20231223
- VernacularTitle:某院新生儿重症监护病房一起CRKP医院感染暴发的流行病学调查
- Author:
Weijie LI
1
;
Liqin CHEN
;
Yaling LI
;
Yonghui HAN
;
Xiaojuan LI
;
Ruogu WANG
Author Information
1. 昆明市儿童医院感染管理科,云南 昆明 650228
- Keywords:
CRKP;
Hospital Infection;
Newborns;
Hospital Infection Outbreak;
Epidemiology
- From:
Journal of Kunming Medical University
2023;44(12):144-149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiological characteristics of an outbreak of carbapenem resistant Klebsiella pneumoniae(CRKP)hospital infection in the neonatal intensive care unit(NICU),and to explore possible causes of the outbreak.Methods Case analysis,epidemiological studies and environmental detection methods were used to investigate the detection of CRKP in the NICU of a hospital from March 11,2022 to May 3,2022,and the causes and corresponding prevention and control measures were analyzed.Results This CRKP outbreak in the NICU occurred in two phases.The first phase was from March 11,2022,to March 30,2022,during which 3 people contracted CRKP hospital infections.The second phase was from April 13,2022,to May 3,2022,during which 4 people contracted CRKP hospital infections.The source of the hospital infection outbreak was patient No.1.All 13 CRKP cases showed sensitivity only to amikacin and tigecycline,with intermediate sensitivity to levofloxacin,and high resistance to other antibiotics.All 13 CRKP cases carried resistant genes for metalloenzymes.After the outbreak,the ward environment was sampled three times,with 35 samples taken in total,and 14 of them tested positive for CRKP.After strict environmental cleaning,disinfection,and multiple control measures,no new hospital infection cases similar to this outbreak were detected after May 13,2022.Conclusion The outbreak of NICU hospital infections may be due to the contamination of the ward environment,medical equipment,and inadequate hand hygiene of medical staff,leading to its spread.Therefore,strict cleaning and disinfection of the environmental surfaces,strengthening hand hygiene of medical staff,and implementing multiple measures can effectively control hospital infections of CRKP.
