Clinical observations on mandibular chronic osteomyelitis: Combination therapy of decortication and intra-arterial infusion chemotherapy.
- Author:
Yuichiro KUROIWA
1
;
Hiroaki MATSUURA
;
Atsushi ABE
;
Mugio KATO
;
Yoshiko ARIJI
;
Kenichi KURITA
Author Information
1. First Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-gakuin University, Japan. kuroiwayuichiro@yahoo.co.jp
- Publication Type:Case Report
- Keywords:
Chronic osteomyelitis;
Diffuse osteosclerosis;
Intra-arterial infusion;
Antibiotic;
Decortication
- MeSH:
Anesthesia, General;
Anti-Bacterial Agents;
Arteries;
Bone Marrow;
Communicable Diseases;
Follow-Up Studies;
Infusions, Intra-Arterial;
Mandible;
Osteomyelitis;
Osteosclerosis;
Recurrence;
Temporal Arteries
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2008;34(3):350-354
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mandibular chronic osteomyelitis with diffuse osteosclerosis is recognized as an intractable infectious disease. We emplyed decortication and intra-arterial infusion of antibiotics in 6 cases. Decortication on the affected mandible was performed with retrocatherization to the superficial temporal artery of affected side under general anesthesia. Antibiotics, IPM/CS or FOMX was used through the artery for 4-11 days. In addition, we administered FOMX, PIPC intravenously for 8-17 days. CT and MRI were taken postoperatively. The postoperative follow-up period ranged from 1 year and 6 months to 2 years and 5 months. Postoperative MR showed that bone marrow signal was recovered to approximately normal in 4 cases. High signal area of bone marrow and osteosclerosis image remained in 2 cases, but showed improvement. The results were satisfactory without recurrence in all of 6 cases.
