Dosimetric study of isolated neuronal networks under 2.6 GHz radiofrequency exposure
10.7644/j.issn.1674-9960.2024.02.003
- VernacularTitle:2.6GHz射频暴露条件下离体神经元网络的剂量学研究
- Author:
Yuqing WANG
1
,
2
;
Xuelong ZHAO
;
Qi LIU
;
Guofu DONG
;
Yu WEI
;
Ni CHEN
;
Xiaoman LIU
;
Changzhen WANG
;
Hongmei ZHOU
Author Information
1. 安徽医科大学基础医学院,合肥 230032
2. 军事科学院军事医学研究院辐射医学研究所,北京 100850
- Keywords:
microelectrode array;
radiofrequency fields;
neuronal networks;
dosimetry;
5G network
- From:
Military Medical Sciences
2024;48(2):95-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the characteristics of dose distribution of neuronal networks in vitro on microelectrode arrays(MEAs)under 2.6 GHz radiofrequency(RF)exposure.Methods The MEAs were coupled with a real-time RF exposure setup,and electromagnetic simulation software was used to calculate the RF dose absorbed in cultured neuronal networks.A fiber-optic temperature probe was used for experimental validation and monitoring of the cell temperature during RF exposure.The MEAs were used to record the electrical activity of neurons.Results For an input power of 1 W,a specific absorption rate(SAR)level of(15.51±2.48)W/kg was calculated,and the variability of the SAR distribution was 16%.In our experimental system,the temperature elevation of neurons was up to 0.15℃for an SAR of 4 W/kg RF exposure.Conclusion The exposure device can provide high SAR efficiency and uniformity in the 2.6 GHz band,which is suitable for studying the real-time effects of RF fields on the electrical activity of neuronal networks in the 5G network band.
