Current status and related research progress of mechanical thrombectomy in large core ischemic stroke of anterior circulation
10.3969/j.issn.1008-794X.2023.12.019
- VernacularTitle:大核心缺血性脑卒中机械取栓现状及相关研究进展
- Author:
Wenxian JIANG
1
;
Shuqing WANG
;
Wenchen TANG
;
Qiyang HU
;
Rong XIAO
;
Yuzhuo KANG
;
Yijie ZHOU
Author Information
1. 541002 广西桂林 桂林市中医医院
- Keywords:
large core cerebral infarction;
small core cerebral infarction;
mechanical thrombectomy
- From:
Journal of Interventional Radiology
2023;32(12):1256-1262
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,mechanical thrombectomy has been the most important research progress in the treatment of acute cerebral infarction,especially the positive results of five endovascular therapy studies in 2015 has rewritten its clinical guidelines.However,the focus of these studies was mainly on the small vessel infarction(SVI),and the inclusion criteria of these studies include the following aspects:ASPECTS ≥6 points,Alberta Stroke Program Early CT Score within 6 hours after stroke onset,the infarct volume＜70 mL within 6-24 hours after stroke onset,and the presence of image mismatch or the presence of mismatch between clinical condition and perfusion imaging.The above studies excluded patients with ASPECTS＜6 points or infarct volume ≥70 mL of large core infarction(LCI).With the continuous progress of the endovascular treatment of acute ischemic stroke(AIS),the mechanical thrombectomy therapy strategy has crossed from the"time window"to the"tissue window",meanwhile,the therapeutic goal of mechanical thrombectomy has also moved from treating SVI to a new era of treating LCI that has been a very hot topic recently.Whether endovascular treatment is beneficial for patients with LCI remains uncertain.This paper aims to make a comprehensive review concerning the relevant research progress in endovascular therapy for anterior circulation large core ischemic stroke,including the imaging determination and study inclusion criteria of LCI,the postoperative blood pressure management,and the factors influencing ineffective recanalization and prognosis.(J Intervent Radiol,2023,32:1256-1262)
