Sonogenetics and its application in military medicine
10.11855/j.issn.0577-7402.0176.2023.0410
- VernacularTitle:声遗传学及其在军事医学中的应用
- Author:
Ying-Tan ZHUANG
1
;
Bo-Yu LUO
;
Xiao-Dong ZHANG
;
Tuo-Yu LIU
;
Xin-Yue FAN
;
Guo-Hua XIA
;
Qing YUAN
;
Bin ZHENG
;
Yue TENG
Author Information
1. 军事科学院军事医学研究院微生物流行病研究所,北京 100071
- Keywords:
sonogenetics;
synthetic biology;
mechanosensitive ion channels;
ultrasonic response;
military medicine
- From:
Medical Journal of Chinese People's Liberation Army
2024;49(3):360-366
- CountryChina
- Language:Chinese
-
Abstract:
Sonogenetics is an emerging synthetic biology technique that uses sound waves to activate mechanosensitive ion channel proteins on the cell surface to regulate cell behavior and function.Due to the widespread presence of mechanically sensitive ion channel systems in cells and the advantages of non-invasion,strong penetrability,high safety and high accuracy of sonogenetics technology,it has great development potential in basic biomedical research and clinical applications,especially in neuronal regulation,tumor mechanism research,sonodynamic therapy and hearing impairment.This review discusses the basic principles of sonogenetics,the development status of sonogenetics and its application in the prevention and treatment of noise-induced hearing loss,summarizes and analyzes the current challenges and future development direction,thus providing a reference for further research and development of sonogenetics in the field of military medicine.
